Eli Lilly and Company
New Regional Research Facility

(Alexandria Real Estate Equities, Inc.)

10290 Campus Point Drive
San Diego, CA 92121

PROJECT COST: $102M Contract Value

Project Highlights:
Redevelopment • Reskin & Gut • High Efficiency Glazing • Complete Central Plant Modernization • Award Winning Metal Art Screen • Award Winning Landscape Design

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This 276,000 SF 4-story building was purchased from Qualcomm in mid-2015. The C&S project, designed by Gensler, included a complete reskin and gut of the existing building. All that remained was the structure and 2-elevators. 4 additional elevators and new egress and communicating stairs were installed. All central plant equipment was replaced and upsized with redundancy to meet higher lab demand. The roof was completely replaced. Gensler designed an art feature consisting of 1,400 metal fins that mimics the DNA strand. California Sheet Metal fabricated and installed this award-winning structure. The TI was designed by HOK and introduced intense laboratory functions that included chemistry and biology, a NexGen robotics lab and a large vivarium. Office, conference, and collaboration spaces were also included. DPR Construction was the General Contractor, who completed this large improvement in 9-months, with Lilly’s occupancy in December of 2016 Certified LEED Gold.

Celgene Corp. – San Diego
Regional Headquarters Relocation

[Now Bristol Meyers Squib]

10300 Campus Point Dr.
San Diego, CA 92121

PROJECT COST: $40M Contract Value

Project Highlights:
Remote Management • MEP Design-Assist • GC RFP • Vivarium • Data Center w/ In-Row Cooling • Evaporative Chiller • LEED Gold

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This 150,000 SF tenant improvement was a result of Celgene’s regional headquarters relocating to a modern and right-sized facility. Due to economic conditions, this was the largest scale life science project going on in San Diego, at the time. With Leadership at Celgene’s corporate headquarters in New Jersey, project management maintained a very high level of coordination with local user groups, while supporting communication protocols with Leadership to advance large decisions, and report on budget and schedule status. This facility includes a luxurious 2-story thru-lobby, office space, intense biology and chemistry lab functions, a large vivarium, and a data center. This project obtained LEED Gold certification.

Sanford Burnham Prebys Medical Discovery Institute – Lake Nona Facility – Orlando

6400 Sanger Road
Orlando, FL 32827

PROJECT COST: $145M Contract Value

Project Highlights:
Satellite Scientific Research Facility • Ground-up Development • State, County, and City Financial Incentive & Agreements • Development Agreement • Chilled Water from Orlando Utility Commission

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Repeat Work with this Client Includes:

a. Orlando Facility – 175,000 SF new development at Lake Nona, FL. The building included biology and chemistry labs, an ultra-high throughput screening center, vivarium, office, and amenity space. Achieved LEED Gold Certification.

b. Orlando Temporary Facility – A 16,000 SF temporary lab and office space converted from a former call center.

c. La Jolla Bldg 10 Lab Tenant Improvement – 8,500 SF office to lab conversion delivered in 7-months. Included open lab, specialty lab spaces, and a high-compute server room for bioinformatics. Design-build.

Illumina – HQ Building 6 – San Diego

[Alexandria Real Estate Equities, Inc.]

5200 Illumina Way
San Diego, CA 92122

PROJECT COST: $110M Contract Value

Project Highlights:
Major Building Size Shift • Separate C&S and TI Design and Construction Teams • Design-Build MEP • Central Plant Expansion • High Bay Space w/ Cold Storage & Freezer Rooms

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Having started at 145,000 SF and converting to 298,000 SF just after schematic design’s, this project included a 5-story building with 2-levels of below-grade parking, a high bay warehouse 4-story wing with covered shipping and receiving docks, and a manufacturing and office tower wing. The building shell consists of a linear curtain wall with a combination of punched openings and stone to contextually match the other campus buildings. DGA and DPR were the main team on the C&S, while Ewing Cole and BN Builders completed the TI. The TI focused heavily on laboratory, manufacturing, cold storage, and high bay warehousing features.

Shire: Regenerative Medicine Business Unit
S. H. O. R. E. Project

(Shire Operations for Regenerative Expansion)

San Diego, CA

PROJECT COST: $60M (Sunk)

Project Highlights:
High Performance Team (Hybrid IPD Contract) • Expedited Permit Approval Process • Pre-Construction Design Assist • Design-Build Curtain Wall • Extensive Cold Storage Space • Process Controls

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As part of an 850,000 SF, 28-acre master planned development in San Diego’s Sorrento Mesa area, Phase 1 of the SHORE (Shire Operations for Regenerative Expansion) project comprised of two buildings. The first was a 250,000 SF Technical Operations Building (TOPs), comprising of manufacturing, laboratory, warehousing, distribution, and a central utility plant. This building was fully designed, permitted, topped out with completed underground utilities and slabs on metal decks. BIM was 90% complete and roughly 60% of procurement was complete, all prior to project shutdown. The second building was a 100,000 SF Commercial Operations Building (COPs) serving more of an administrative function for the campus. This building, while only designed, was planned to contain office, conference and training functions, a fitness center, and a cafeteria.

La Jolla Institute for Allergy & Immunology
New Facility –  La Jolla

9420 Athena Circle
La Jolla, CA 92037

PROJECT COST: $43M Contract Value

Project Highlights:
Ground-up Development • Non-Profit Partnership with Private Pharma • Ground Lease w/ UCSD • Escrow Funds Distribution • Extensive Stone Tile Install

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This 185,000 GSF facility is 3-stories high with a basement. While the basement contains below-grade parking and 13,000 SF vivarium space, the above-grade levels house office, conference space and auditorium, biology and chemistry labs, tissue culture and flow cytometry space, microscopy, and more. LJI maintains a longstanding partnership with Kyowa Hakko Kirin (Japanese pharmaceutical company), who funded this project. Located on UCSD’s Science Research Park, UCSD played a role in this development, including regulatory review and inspections. DPR Construction was the General Contractor and Delawie was the Architect. FF&E, including scientific equipment, was separately funded, but managed holistically.

a. 3rd Floor Office Expansion – 4,000 SF buildout, & HVAC infrastructure upgrades.

b. GLP Lab – 2,500 SF GLP lab Buildout for drug testing.

c. 2nd Floor Lab Buildout – 7,800 SF new lab space with cascading cold rooms.

d. RNAi Lab Buildout – 4,000 SF lab TI that included multiple tissue culture spaces.

Fate Therapeutics – Facility Expansion

[Alexandria Real Estate Equities, Inc.]

3535 General Atomics Ct.
San Diego, CA 92121

PROJECT COST: $9M Contract Value

Project Highlights:
Turnkey TI • Complete Gut • Lab/Office Build • Exposed Ceilings in Office • New Kitchen/Break Area • cGMP Clean Labs • C&S Upgrades • AHU Replacement

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Provided project management services for what began as a C&S renovation and spec suite buildout. Roughly 50% through construction, the project scope changed to accommodate a new plan for the Fate expansion. This 20,000 sf space was designed and permitted twice, with minimal overall schedule impact. As a turnkey delivery method, the space included biology lab, tissue culture space, validated clean lab (Iso 7 & 8), high-end conference, collaboration, and break space that extends outside, and open office.

Inception Sciences
Corporate Relocation & Building Remodel

[Alexandria Real Estate Equities, Inc.]

5677 Nancy Ridge Dr.
San Diego, CA 92121

PROJECT COST: $8M Contract Value

Project Highlights:
C&S Improvements • Turnkey TI • New MEP Systems • Biology/Chemistry/Vivarium • Mezzanine Build for Office & Equipment • Exterior Improvements

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This existing 30,000 sf tilt-up building was intended to serve as Inception’s new home. The project was managed in two separate projects, a C&S project and a turnkey TI project specifically for Inception Sciences. The C&S effort included the replacement of perimeter glazing, installation of ipe wood treatments at key areas, all new landscaping, a new roof, and new interior stairs to support newly constructed mezzanine structures. The TI focused on the development of biology and chemistry lab space, a new vivarium, open office and meeting space, and break area.

Sanford Consortium for Regenerative Medicine

2880 Torrey Pines Scenic Dr.
La Jolla, CA 92037

PROJECT COST: $85M Contract Value

Project Highlights:
P3 – Public Private Partnerships Delivery • Cast-in-Place Concrete Structure • Perimeter Shear Wall Support
• 2-Story Amenities Structure • Linear Equipment Inner-connections • Cantilevered Perimeter Office Pods •
Chilled Beam Design

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This 150,000 SF, 4-story cast-in-place concrete laboratory structure serves as a research collaborative between UCSD, La Jolla Institute for Allergy & Immunology, the Salk Institute, and the Sanford Burnham Prebys Medical Discovery Institute. This building includes a 24,000 SF vivarium. A separate 2-story steel-framed structure includes a café and 150-seat auditorium. This project was certified LEED Gold.

As a result of this project being funded publicly via CIRM, as well as through private donations, and being located on University of California San Diego property, management efforts for this project were focused on investor representation, with a scope of services that included monthly reporting on cash flow spend vs. work-in-place, contract and cost consulting, and change order oversight. Additional scope included move management to develop an RFP to adequately select a move company and coordinate the moves of 28 research groups from four different institutions.

Salk Institute for Biological Studies
Central Plant Upgrades

10010 N. Torrey Pines Rd.
La Jolla, CA 92037

PROJECT COST: $22M Contract Value

Project Highlights:
Central Plant Upgrade • Chillers & Towers Replacement • Switchgear Replacement • Emergency Generator Addition • Critical Utilities Shutdown Coordination

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Investor representation role supporting the Salk Board of Directors. This $22M project was funded via a bond whereas, it was important to the Board that financial reporting be completed on a monthly basis, to validate the proper spend. Efforts required to develop monthly reports include attending weekly OAC meetings, weekly job walks, detailed pay app reviews, and continued change order status reviews.

Genentech – Nimo Facility Shutdown

One Antibody Way
Oceanside, CA 92056

PROJECT COST: Confidential

Project Highlights:
Multi-Project Scheduling • Daily Project Status Meetings • Detailed Task-Driven Management • Project Team Oversight • Cross-Departmental Collaboration

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Provided management and oversight of 32 construction projects that had to be executed within a 2-week window, supporting product transition to manufacture the drug Avastin. Through 6-months of planning the leadership team developed scopes of work, tasks definition and duration, and risk assessment. Working closely with up to six PM and contractor teams, as well as numerous internal departments, like Maintenance, QC, Validation, Upstream, Downstream, etc., the successful execution of this effort was fully dependent upon the in-depth pre-planning. This project was honored as the ISPE/Interphex as 2007 Facility of the Year Winner for Project Execution.

VIDA – 11045 Roselle

[Alexandria Real Estate Equities, Inc.]

11045 Roselle
San Diego, CA 92121

PROJECT COST: $11.3M Project Value

Project Highlights:
Redevelopment • Reskin & Gut • New Class A Roof System • Lab/Office Conversion • 3-Spec Suites • Common Conferencing • Through-Lobby • Restaurant

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This 29,754 square foot building was built in the mid-80’s and served as the previous home of Tandem Diabetes. This project’s C&S was designed by LPA, interiors by DGA, and constructed by BN Builders. Intersect performed all project management duties for Alexandria.

The building was gutted, and the entire street-facing side of the building was reskinned with new glazing and additional windows added in the back. The roof of the building was completely replaced with sprayed-on polyurethane foam, which also captured necessary T24 insulation requirements.

3-laboratory/office speculative suites were constructed. The average size of each of the suites was roughly 8,000 square feet. By completion of the project, VelosBio had occupied two of the suites and design was underway for the 3rd, to be occupied by Encodia. All of the interiors were supported by a new VRF system and package units, with all new primary and standby electrical distribution.

The TI’s also included a large multi-purpose conferencing space, a uniquely finished through lobby, and a restaurant space operated by City Tacos.

ActivX Biosciences
Facility Renovation & Relocation

[HCP, Inc./Healthpeak Properties, Inc.]

11025 N. Torrey Pines Rd.
La Jolla, CA 92037

PROJECT COST: $4M Contract Value

Project Highlights:
Lab & Office Remodel • Supplemental Cooling & Power
• In-Depth Assessment of Existing Conditions •
ADA Upgrades

Sherpa Clinical Packaging

(now PCI Pharma Services)

Facility Renovation & Relocation

6166 Nancy Ridge Dr.
San Diego, CA 92121

PROJECT COST: $2.5M Contract Value

Project Highlights:
cGMP Storage, Cold Storage, & Packaging Space •
Offices • Emergency Generator

Takeda California – New Vivarium

10275 Science Center Dr.
San Diego, CA 92121

PROJECT COST: $6M Contract Value

Project Highlights:
7,800 SF Vivarium Build • Clean & Dirty Wash •
Necropsy • New AHU & Exhaust • New Emergency
Generator • AAALAC Certified

Molecular Medicine BioServices (SAFC)
New cGMP Facility

[Now Millipore Sigma]

Carlsbad, CA

PROJECT COST: $3.8M Contract Value

Project Highlights:
12,000 SF • ISO 7 & 8 Cleanrooms • Validated
Facility • CMO Operation • Mezzanine Structure
Supporting Equipment

SkyePharma (Pacira)
Depodur cGMP Manufacturing Facility

10450 Science Center Dr.
San Diego, CA 92121

PROJECT COST: $3.5M Contract Value

Project Highlights:
20,000 SF • Cascading ISO Level Cleanrooms • Analytical & QC Lab Upgrades • Fan-Powered HEPA Filtration • BAS Conversion to Validated System

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